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Table 8 Interpretation of the tuberculin sensitivity (Mantoux) test*

  Induration
Clinical context <5 mm 5-10 mm 10-20 mm >25 mm
Screening, non-endemic population Negative Suspicious of infection† 90% of patients have infection Virtually all have infection
Screening, endemic population Negative Consistent with past infection† Suspicious of infection Suggestive of infection
Following BCG vaccination Negative Expected Suspicious of infection Suggestive of infection
Chest X-ray suggesting past infection Negative Consistent with past infection† Suspicious of infection Suggestive of infection
Suspicious clinical findings or contact with active tuberculosis

Negative

Suspicious of infection 90% of patients have infection Virtually all have infection

* Intradermal injection of 10 Tuberculin units of purified protein derivative (PPD).
† May also be due to cross-reactivity with other mycobacterial species.

Serial tuberculin testing may produce an augmented reaction (booster phenomenon) in those previously sensitised by infection or BCG vaccination.

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