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Paroxysmal nocturnal haemoglobinuria
| Paroxysmal nocturnal haemoglobinuria | FBC , blood film , differential WCC , platelet count ; direct antiglobulin test ; reticulocyte count . Sucrose lysis test ; acidified serum (Ham) test ; flow cytometry to detect abnormal red cell, leucocyte, platelet subpopulations. Haemosiderin - urine . Bone marrow aspiration and trephine biopsy . |
| Anaemia | |
| Thrombosis | |
| Abdominal pain | |
| Progression to | |
| Myelodysplasia | |
| Acute leukaemia |
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