PARIETAL CELL ANTIBODIES - serum

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Specimen: 10 mL blood in plain tube.

Method: Indirect IF.

Reference Interval: Not detected.

Application: A supportive, but not diagnostic, test for pernicious anaemia.

Interpretation: Antibodies react with sub-units of the gastric parietal cell proton pump. Positive in 80% of patients with pernicious anaemia and in 40-50% of patients with other organ specific autoimmune diseases. See INTRINSIC FACTOR ANTIBODIES .

Reference: Yao Y et al. J Fam Pract 1992; 35: 524-528.

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