MITOCHONDRIAL ANTIBODIES - serum

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Specimen: 5 mL blood in plain tube.

Method: Indirect IF.

Reference Interval: Qualitative test; positive is significant.

Application: Diagnosis of primary biliary cirrhosis (PBC).

Interpretation: A positive result at high titre is highly sensitive and specific for PBC.

Reference: Doniach D. In: Schwartz RS ed. Progress in Clinical Immunology. Grune & Stratton 1972.

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