ISOHAEMAGGLUTININ TITRES - serum

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Specimen: 5 mL blood in plain tube.

Method: Serum reacted, over a range of dilutions, with red cells of known blood group.

Reference Interval: Consult laboratory.

Application: Investigation of immune deficiency, esp humoral deficiency.

Interpretation: Absent or low titres of anti-A or anti-B isohaemagglutinins, in individuals of the appropriate ABO blood group, suggests humoral immune deficiency eg Wiskott-Aldrich syndrome.

Reference: WHO Scientific Group. Clin Exp Immunol 1995; 99 (suppl 1) 8.

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