AMYLASE - urine

---

Specimen: Timed or 24 hour urine collection with no preservative.

Method: Spectrophotometry.

Reference Interval: Method dependent; consult pathologist.

Application: Rarely indicated: suspected acute pancreatitis with normal serum amylase; persistent significant elevation of serum amylase, if macroamylasaemia is suspected.

Interpretation: Urine level may be increased in acute pancreatitis at a time when the serum amylase level has returned to within the reference interval. High serum and low urine amylase levels are seen in macroamylasaemia. Use of an amylase/creatinine clearance ratio is not recommended.

Reference: Clavé P et al. Clin Chem 1995; 41: 1129-1134.

---