AMOEBA ANTIBODIES - serum
Specimen: 5-10 mL blood
in plain tube.
Method: IHA, CIE, ID.
Application: Diagnosis of extraintestinal amoebiasis eg liver abscess.
Interpretation: Most patients with diarrhoea, and asymptomatic carriers, have
negative serology. IHA titres >128 support a diagnosis of extraintestinal amoebiasis
caused by Entamoeba histolytica. Antibody levels remain elevated for prolonged
periods. A four fold rise in titre is convincing evidence of recent infection.
Reference: Ravdin JI and Petri WA Jr. In: Mandell GL et al eds. Principles
and Practice of Infectious Diseases. 4th ed. Churchill Livingstone 1995.
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